Dr. Michael "Robby" Robinavitch (Noah Wyle) confronts hospital budget cuts threatening patient care. Dr. Heather Collins (Tracy Ifeachor) faces a personal crisis impacting her duties, while Dr. Samira Mohan (Supriya Ganesh) uncovers a misdiagnosis with life-threatening implications. Amidst the chaos, new resident Dr. Trinity Santos (Isa Briones) grapples with a critical mistake, questioning her medical aptitude.